Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light.
Identifieur interne : 000468 ( Main/Exploration ); précédent : 000467; suivant : 000469Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light.
Auteurs : Jesse J. Fryk ; Denese C. Marks ; Jody Hobson-Peters [Australie] ; Daniel Watterson [Australie] ; Roy A. Hall [Australie] ; Paul R. Young [Australie] ; Stefan Reichenberg [Allemagne] ; Frank Tolksdorf [Allemagne] ; Chryslain Sumian [France] ; Ute Gravemann [Allemagne] ; Axel Seltsam [Allemagne] ; Helen M. FaddySource :
- Transfusion [ 1537-2995 ] ; 2017.
Abstract
Zika virus (ZIKV) has emerged as a potential threat to transfusion safety worldwide. Pathogen inactivation is one approach to manage this risk. In this study, the efficacy of the THERAFLEX UV-Platelets system and THERAFLEX MB-Plasma system to inactivate ZIKV in platelet concentrates (PCs) and plasma was investigated.
DOI: 10.1111/trf.14256
PubMed: 28718518
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Zika virus (ZIKV) has emerged as a potential threat to transfusion safety worldwide. Pathogen inactivation is one approach to manage this risk. In this study, the efficacy of the THERAFLEX UV-Platelets system and THERAFLEX MB-Plasma system to inactivate ZIKV in platelet concentrates (PCs) and plasma was investigated.</div>
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